Increasing age is the most important risk factor for most cancers. Tumor breaks through the basement membrane and invades the cervical stroma.Д®xtension of the tumor in the cervix may ultimately manifest as ulceration,Д®xophytic tumor, or extensive infiltration of underlying tissue, including Situ to invasive in a period of less than 1 year. However, in about 10% of patients, lesions can progress from in Longitudinal studies have shown that in patients with untreated in situД¬ervical cancer, 30% to 70% will develop invasive carcinoma over a period of 10 Which can subsequently become invasive cancer. The precursor lesion isДysplasia: cervical intraepithelial neoplasia (CIN) or adenocarcinoma in situ, Enlarge PathogenesisД¬ervical carcinoma has its origins at the squamous-columnar junction it can involve the outer squamous cells, the inner glandular cells, or both. Most of precancerous and cancerous changes arise in this zone. The transition between squamous cells and columnar cells is an area termed the squamo-columnar junction. The cervix is lined by two types of epithelial cells: squamous cells at the outer aspect, and columnar, glandular cells along the inner canal.

The endocervical canal beyond the internal os is termed the endometrial canal. The narrowing marks the transition from the cervix to the uterine body.

At the upper aspect of the endocervical canal is the internal os, a narrowing of the endocervical canal. The os is the beginning of the endocervical canal, which forms the inner aspect of the cervix. The opening of the cervix is termed the external os. The portio of the cervix is the part of the cervix that is visible on vaginal inspection. The uterine cervix is a cylindrical, fibrous organ that is an average of 3 to 4 cm in length. The uterine cervix is contiguous with the uterine body, and it acts as the opening to the body of the uterus.

Ls 17 version